Houston McCullough
May 12, 2026
Nerveli was founded for chronic pain sufferers, by chronic pain sufferers.
Meet Leon Jacobson
Founder & CEO
Living with chronic pain. 23 doctors and he still couldn’t bend over to play with his son.
Leon didn’t just want relief– he wanted his life back.
So he partnered with pain psychologists, pain scientists, physicians, and data scientists to build what was missing: science-backed, daily support for pain between visits. That work became Nerveli.
Nerveli can help
We believe pain is real
No convincing. No proving. No minimizing.
We respect complexity
Pain isn’t one-size-fits-all. Neither is support.
We lead with science and humility
Evidence matters. So does listening.
We support, not replace, care
Work alongside providers.
We build for real life
Progress that fits into imperfect days.
Where does the system fall short?
Pain is complex, but care is often fragmented. Appointments are short, answers are unclear, and most people are left to manage pain alone between visits.
What actually helps?
Research and lived experience show that understanding pain– how it’s influenced by stress, habits, and the nervous system– can reduce suffering. Daily support matters.
What can we build?
Nerveli was built to support people in the moments care often doesn’t: between appointments, during flare-ups, and on the days pain feels invisible.


Understand your pain → get daily support → make progress over time.
News
5 min read
Nerveli and the American Chronic Pain Association Announce Landmark Partnership to Transform Chronic Pain Care
Partnership Unites Digital Innovation with Over Four Decades of Patient Advocacy to Deliver Education, Community, and Hope
Houston McCullough
May 12, 2026

News
5 min read
Ten Startups to Watch.
Nerveli was recognized by the Dallas Business Journal as a top Dallas-Fort Worth startup. Co-founder Leon Jacobson is transforming chronic pain care with science-based, AI-powered technology that empowers patients to monitor and understand their pain. Backed by $880K from investors and supported by Techstars and MassChallenge, Nerveli is piloting with Trinity Health. A freemium version launches this April. Read the full article at Dallas Business Journal.
Holden Wilen and Will Anderson
March 30, 2026
Advisory board members
We’re lucky to be supported by some of the best advisors in the world.